New treatment approach for cervical cancer using accelerated brachytherapy and chemoradiation
Official title: Accelerated Brachytherapy Forward Chemoradiation Therapy (ABC-RT) for Cervical Cancer
Funded at Washington University · NIH-10976688 · Data updated 2026-11-12
This study is exploring a new way to treat cervical cancer by combining a special type of radiation therapy with chemotherapy to boost the immune system and lower the chances of the cancer coming back, and it's designed for patients who want to learn about innovative treatment options.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | August 15, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $634,894 |
| NIH project number | 1R37CA287204-01A1 |
| Project ID | NIH-10976688 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with cervical cancer who are undergoing or are eligible for chemoradiation therapy.
✕Less likely to help
Patients with early-stage cervical cancer who are not receiving chemoradiation therapy may not benefit from this research.
What this research studies
This research investigates a novel treatment method for cervical cancer that combines accelerated brachytherapy with chemoradiation therapy. The approach aims to enhance the immune response and reduce the risk of cancer recurrence by targeting the tumor environment and improving systemic control. By studying preclinical models and patient specimens, the research seeks to identify how this combined therapy can stimulate immune responses more effectively than current standard treatments. Patients may be monitored for changes in tumor markers and immune cell activity during the treatment process.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and reduced recurrence of cervical cancer for patients.
How similar studies have gone: Previous research has shown promising results with similar approaches that enhance immune responses in cancer treatment, indicating potential for success in this novel method.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Markovina, Stephanie — Washington University
- Study coordinator: Markovina, Stephanie
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.