New treatment approach for breast cancer in Hispanic and Latina women.
Official title: Targeting centrosome-mitotic kinases as a novel therapeutic approach against breast cancers in Hispanic/Latinas. Supplement1
Funded at Ponce School of Medicine · NIH-10993750 · Data updated 2026-11-12
This study is looking for new treatments for aggressive breast cancer, especially in Hispanic and Latina women, by exploring how certain proteins in tumors affect cancer growth, with the hope of finding better ways to help those facing this challenge.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ponce School of Medicine NIH-funded |
| Lab location | 1 site (Ponce, United States) |
| Project start | September 15, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $117,166 |
| NIH project number | 3R01CA266046-03S1 |
| Project ID | NIH-10993750 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Hispanic and Latina women diagnosed with triple-negative breast cancer.
✕Less likely to help
Patients with non-aggressive forms of breast cancer or those outside the Hispanic and Latina demographic may not benefit from this research.
What this research studies
This research focuses on developing new therapies for breast cancer, particularly targeting aggressive forms like triple-negative breast cancer (TNBC) that disproportionately affect Hispanic and Latina women. The study investigates specific kinases, TTK and Nek2, which are found to be overexpressed in breast tumors of women with African ancestry. By understanding how these kinases contribute to cancer progression, the research aims to create targeted treatments that could improve outcomes for these patients. The approach includes analyzing tumor samples and exploring the biological mechanisms behind cancer aggressiveness.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for breast cancer in Hispanic and Latina women, potentially reducing mortality rates.
How similar studies have gone: Previous research has shown promise in targeting specific kinases in cancer treatment, indicating potential for success in this novel approach.
Where this research is happening
-
Ponce School of Medicine
Ponce, United States Active
Researchers
- Principal investigator: Saavedra, Harold I — Ponce School of Medicine
- Study coordinator: Saavedra, Harold I
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.