New treatment approach for atrial fibrillation using metabolic therapy
Official title: Metabolic therapy for atrial fibrillation
Funded at Cleveland VA Medical Research/ed/fdn · NIH-10975588 · Data updated 2026-11-12
This study is testing a new treatment that aims to help people with atrial fibrillation by focusing on improving health issues like obesity and diabetes, which can make the heart rhythm problem worse.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland VA Medical Research/ed/fdn NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $100,050 |
| NIH project number | 1R21HL170269-01A1 |
| Project ID | NIH-10975588 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with atrial fibrillation, particularly those with associated cardiometabolic risk factors.
✕Less likely to help
Patients with atrial fibrillation who do not have any underlying metabolic conditions or those who are not eligible for metabolic therapy may not benefit from this research.
What this research studies
This research investigates a novel metabolic therapy aimed at treating atrial fibrillation (AF), a common heart rhythm disorder affecting millions. The approach focuses on addressing underlying cardiometabolic risk factors such as obesity and diabetes, which may contribute to the progression of AF. By exploring the effectiveness of this therapy, the research seeks to improve the management of AF and reduce the recurrence of symptoms. Patients may be monitored for changes in their condition and overall heart health as part of the treatment process.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for atrial fibrillation, potentially reducing symptoms and improving quality of life for patients.
How similar studies have gone: Previous studies have shown promising results with metabolic interventions in managing atrial fibrillation, suggesting that this approach may be effective.
Where this research is happening
-
Cleveland VA Medical Research/ed/fdn
Cleveland, United States Active
Researchers
- Principal investigator: Sundaram, Varun — Cleveland VA Medical Research/ed/fdn
- Study coordinator: Sundaram, Varun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.