New tools to visualize how cancer cells communicate using chemokines
Integrated Imaging Tools for Intercellular Chemokine Signalling
['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-10903923
This study is looking at how certain molecules called chemokines affect cancer cells and their interactions with other cells, using new imaging tools to see these processes in real-time, with the hope of improving cancer treatments that target these signals.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-10903923 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how chemokines, which are signaling molecules, influence the behavior of cancer cells and their interactions with surrounding cells. By developing advanced imaging tools, the research aims to track the distribution and activity of these chemokines in real-time within living systems. This approach will help uncover the complex dynamics of chemokine signaling that regulate cancer cell growth, movement, and immune response. Ultimately, the goal is to enhance the effectiveness of therapies targeting chemokine signaling in cancer treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with breast cancer or other cancers where chemokine signaling plays a significant role.
Not a fit: Patients with non-cancerous conditions or those whose cancer does not involve chemokine signaling may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments by improving our understanding of how to manipulate chemokine signaling.
How similar studies have performed: Previous research has shown promise in targeting chemokine signaling in cancer, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LUKER, GARY D — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: LUKER, GARY D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Breast Cancer, Breast Cancer Cell