New tests to monitor COVID-19 in patients with blood cancers
Official title: Immuno-Serological Assays for Monitoring COVID19 in Patients with Hematologic Malignancies
Funded at Yale University · NIH-10855033 · Data updated 2026-11-12
This study is looking at new ways to check how well the immune system is responding to COVID-19 in patients with blood cancers, helping doctors understand their condition better and improve their treatment.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 30, 2020 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $1,137,992 |
| NIH project number | 3U01CA260507-02S2 |
| Project ID | NIH-10855033 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with hematologic malignancies who are also infected with or at risk of COVID-19.
✕Less likely to help
Patients without hematologic malignancies or those not infected with COVID-19 may not benefit from this research.
What this research studies
This research focuses on developing and validating innovative immuno-serological assays to monitor COVID-19 in patients with hematologic malignancies, who are at a higher risk of severe disease. The approach involves creating a high-density antibody barcode microchip to measure various immune markers and antibodies in the blood, as well as assessing immune cell function through single-cell analysis. By conducting longitudinal measurements, the research aims to provide insights into the immune response and disease progression in these patients. This comprehensive testing could help tailor treatment and improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring and management of COVID-19 in patients with blood cancers, potentially improving their survival rates.
How similar studies have gone: Other research has shown promise in using immuno-serological assays for monitoring infections, suggesting that this approach could be effective in this context as well.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Fan, Rong — Yale University
- Study coordinator: Fan, Rong
Related research
Other NIH-funded projects on the same topics.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.