New tests to monitor COVID-19 in patients with blood cancers
Immuno-Serological Assays for Monitoring COVID19 in Patients with Hematologic Malignancies
This study is looking at new ways to check how well the immune system is responding to COVID-19 in patients with blood cancers, helping doctors understand their condition better and improve their treatment.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10855033 on NIH RePORTER |
What this research studies
This research focuses on developing and validating innovative immuno-serological assays to monitor COVID-19 in patients with hematologic malignancies, who are at a higher risk of severe disease. The approach involves creating a high-density antibody barcode microchip to measure various immune markers and antibodies in the blood, as well as assessing immune cell function through single-cell analysis. By conducting longitudinal measurements, the research aims to provide insights into the immune response and disease progression in these patients. This comprehensive testing could help tailor treatment and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with hematologic malignancies who are also infected with or at risk of COVID-19.
Not a fit: Patients without hematologic malignancies or those not infected with COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring and management of COVID-19 in patients with blood cancers, potentially improving their survival rates.
How similar studies have performed: Other research has shown promise in using immuno-serological assays for monitoring infections, suggesting that this approach could be effective in this context as well.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Fan, Rong — Yale University
- Study coordinator: Fan, Rong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.