New tests to monitor COVID-19 in patients with blood cancers
Official title: Immuno-Serological Assays for Monitoring COVID19 in Patients with Hematologic Malignancies
Funded at Yale University · NIH-10680624 · Data updated 2026-11-12
This study is looking to create new blood tests that can help doctors keep an eye on how COVID-19 affects patients with blood cancers, so they can better understand their immune responses and improve care for those at higher risk.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 30, 2020 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $711,873 |
| NIH project number | 4U01CA260507-02 |
| Project ID | NIH-10680624 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with hematologic malignancies who are also infected with or at risk for COVID-19.
✕Less likely to help
Patients without hematologic malignancies or those not affected by COVID-19 may not benefit from this research.
What this research studies
This research focuses on developing and validating innovative immuno-serological assays to monitor COVID-19 in patients with hematologic malignancies, who are at higher risk for severe disease. The approach includes creating a high-density antibody barcode array microchip to measure various immune markers and antibodies in the blood. Additionally, a microchip assay will assess immune cell function and identify specific immune responses. By longitudinally tracking these markers, the research aims to improve understanding of COVID-19's impact on this vulnerable population.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring and management of COVID-19 in patients with blood cancers, potentially improving their health outcomes.
How similar studies have gone: Other research has shown promise in using similar immuno-serological assays for monitoring immune responses in various diseases, suggesting potential success for this approach.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Fan, Rong — Yale University
- Study coordinator: Fan, Rong
Related research
Other NIH-funded projects on the same topics.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.