New test for personalized treatment of head and neck cancer
Novel OrganoPET Assay for Precision Therapy of Head and Neck Cancer
This study is working on better treatments for head and neck cancer by creating mini versions of tumors from patients, so doctors can see how different treatments might work best for each person's unique cancer.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10880693 on NIH RePORTER |
What this research studies
This research focuses on improving treatment for head and neck squamous cell carcinomas (HNSCCs), which are known for their complexity and resistance to therapies. The project aims to develop a high-throughput platform to create patient-derived tumor organoids, allowing researchers to study how different genetic and epigenetic profiles affect responses to drugs and radiation. By correlating treatment responses with DNA methylation patterns, the research seeks to enhance precision in clinical decision-making for HNSCC patients. This innovative approach could lead to more effective, personalized therapies based on individual tumor characteristics.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with head and neck squamous cell carcinoma who are facing challenges with current treatment options.
Not a fit: Patients with other types of cancers or those who do not have head and neck squamous cell carcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with head and neck cancer.
How similar studies have performed: Previous research has shown promise in using similar approaches to classify cancer subtypes and tailor treatments, indicating potential for success in this novel application.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Khan, Syamantak — Stanford University
- Study coordinator: Khan, Syamantak
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.