New technology to improve access to archived tissue samples for studying genetic changes
Development of a cavitation enhancement technology to access archived tissues for epigenetic-based biomedical research
['FUNDING_R01'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-10821375
This study is working on a new method to help scientists get better DNA from old tissue samples, which could lead to improved understanding and treatments for brain disorders and cancers that affect patients like you.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF NORTH CAROLINA CHAPEL HILL (nih funded) |
| Locations | 1 site (CHAPEL HILL, UNITED STATES) |
| Trial ID | NIH-10821375 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a novel cavitation enhancement technology that simplifies the process of extracting high-quality chromatin from archived tissue samples. By improving the efficiency of genomic DNA fragmentation, this technology aims to make it easier for researchers to study epigenetic mechanisms that are crucial for understanding various neurological disorders and cancers. Patients may benefit from advancements in diagnostic techniques and treatments that arise from better insights into these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological disorders such as intellectual disabilities, autism, or epilepsy, as well as those affected by certain types of cancer.
Not a fit: Patients who do not have neurological disorders or cancers related to epigenetic changes may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods and treatments for neurological disorders and cancers linked to epigenetic changes.
How similar studies have performed: Other research has shown success with innovative technologies in epigenetics, indicating that this approach has the potential to yield significant advancements.
Where this research is happening
CHAPEL HILL, UNITED STATES
- UNIV OF NORTH CAROLINA CHAPEL HILL — CHAPEL HILL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PATTENDEN, SAMANTHA GAIL — UNIV OF NORTH CAROLINA CHAPEL HILL
- Study coordinator: PATTENDEN, SAMANTHA GAIL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.