New technology for treating inoperable liver tumors

Feasibility of a Multi-Phase Algorithmic Non-Thermal Ablation Technology for the Treatment of Inoperable Tumors

NIH-funded research Gradient Medical, INC. · NIH-10547371

This study is testing a new, gentle treatment called PACE that uses quick electrical pulses to help destroy hard-to-reach liver tumors, and it's designed for patients whose tumors can't be removed with surgery.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionGradient Medical, INC. NIH-funded
Lab location1 site (Cary, United States)
Project IDNIH-10547371 on NIH RePORTER

What this research studies

This research investigates a novel minimally invasive technique called Phased Algorithmically Controlled Electrotherapy (PACE) for treating inoperable liver tumors. The approach uses ultrashort high-intensity electrical pulses to disrupt cancer cells, leading to cell death. The study aims to develop a specialized pulse generation system and assess how effectively it can target liver tumors. Patients with liver tumors that cannot be surgically removed may benefit from this innovative treatment method.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with inoperable liver tumors who are not suitable for surgical resection.

Not a fit: Patients with operable liver tumors or those who have other medical conditions that preclude them from receiving this type of treatment may not benefit.

Why it matters

Potential benefit: If successful, this research could provide a new treatment option for patients with inoperable liver tumors, potentially improving survival rates.

How similar studies have performed: While this approach is innovative, similar techniques using electrical pulses for tumor treatment have shown promise in preliminary studies.

Where this research is happening

Cary, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.