New technology for recording heart cell electrical activity
Multi-electroplasmonic nanoantenna arrays for wireless transmembrane-level recording of cardiomyocyte action potentials with sub-micrometer resolution
['FUNDING_R01'] · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · NIH-10981983
This study is testing a new technology that uses tiny sensors to closely watch how heart cells work, which could help doctors understand heart problems better and create new treatments for patients with heart conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-10981983 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a novel technology called multi-electroplasmonic nanoantenna arrays (MENAs) to monitor the electrical activity of heart cells, known as cardiomyocytes, with high precision. By using these nanoantennas, researchers aim to overcome current limitations in measuring action potentials, which are crucial for understanding heart rhythms and potential arrhythmias. The approach involves creating a wireless system that allows for long-term observation of heart cell behavior at a microscopic level, which could lead to better insights into cardiac diseases and the development of new treatments. Patients may benefit from advancements in therapies targeting heart conditions as a result of this research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with known cardiac arrhythmias or those at high risk for developing cardiovascular diseases.
Not a fit: Patients with non-cardiac related health issues or those who do not have any cardiovascular risk factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of cardiac arrhythmias, potentially reducing morbidity and mortality associated with cardiovascular diseases.
How similar studies have performed: While the approach of using nanoantenna technology for electrophysiological studies is innovative, similar methodologies have shown promise in other areas of biomedical research, indicating potential for success in this application.
Where this research is happening
CAMBRIDGE, UNITED STATES
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SARKAR, DEBLINA — MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Study coordinator: SARKAR, DEBLINA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cardiac Diseases, Cardiac Disorders