NIH-funded research NIH-funded research

New technology for quick liver function tests at home

Official title: Tethered Enzyme Technology for PoC and At-home Real-time Monitoring of Liver Function

Funded at Tet Medical · NIH-10822326 · Data updated 2026-11-12

This study is working on a new way to quickly check liver enzyme levels, like AST and ALT, so that people can easily test for liver damage either at home or at a clinic, making it especially helpful for those who have trouble getting to a doctor.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionTet Medical
NIH-funded
Lab location1 site (Ithaca, UNITED STATES)
Project startDecember 15, 2023
Project endDecember 14, 2025
Funding year2024
Award (this year)$324,962
NIH project number1R41TR004880-01
Project IDNIH-10822326 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals at risk for liver damage, such as those taking medications known to affect liver function or those with existing liver conditions.

Less likely to help

Patients with stable liver function and no risk factors for liver injury may not benefit from this research.

What this research studies

This research focuses on developing a tethered enzyme technology that allows for rapid testing of liver enzyme levels either at a healthcare facility or in the comfort of patients' homes. By measuring enzymes like AST and ALT, which indicate liver damage, this technology aims to provide timely monitoring of drug-induced liver injury and other liver conditions. The goal is to simplify the testing process, making it more accessible for patients, especially those with mobility issues or those living far from medical facilities. This innovative approach could significantly reduce the burden of traditional testing methods, which often require clinic visits and lengthy wait times for results.

Why it matters

Potential benefit: If successful, this research could enable patients to monitor their liver health more conveniently and frequently, leading to quicker interventions when issues arise.

How similar studies have gone: Similar approaches in point-of-care testing have shown promise in other areas of healthcare, suggesting potential for success in this novel application.

Where this research is happening

  • Tet Medical
    Ithaca, United States
    Active

Researchers

  • Principal investigator: Cohen, Roy — Tet Medical
  • Study coordinator: Cohen, Roy

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.