New technology for non-invasive monitoring of deep tissue blood flow

TRD2: Interferometric Near Infrared Spectroscopy (iNIRS)

NIH-funded research University of California at Davis · NIH-11105987

This study is testing a new, easy way to check blood flow in deep tissues using special light, which could help people with brain and other health issues by providing better and safer monitoring without any needles or surgery.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-11105987 on NIH RePORTER

What this research studies

This research focuses on developing a novel non-invasive technique called interferometric diffuse optical spectroscopy (iDOS) to monitor blood flow in deep tissues using near-infrared light. The approach utilizes advanced sensors to provide continuous and accurate measurements of blood flow dynamics, addressing limitations of existing technologies. By employing low-cost CMOS sensors, the research aims to create a more accessible and effective method for monitoring conditions related to brain and other deep tissue health. Patients may benefit from improved diagnostic capabilities and monitoring of their conditions without the need for invasive procedures.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who may require monitoring of deep tissue blood flow, particularly in the brain.

Not a fit: Patients with conditions that do not involve deep tissue blood flow monitoring may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and accessible monitoring of blood flow in patients, enhancing diagnosis and treatment of various medical conditions.

How similar studies have performed: Previous research in non-invasive optical monitoring techniques has shown promise, but this specific approach using iDOS is relatively novel.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.