New technology for measuring large biomolecules in cells
Multiplexed Charge Detection Mass Spectrometer for Extended Mass and Collisional Cross Section Measurements
This study is working on new ways to look closely at large molecules in our cells that are important for how our bodies function, which could help scientists create better treatments for various health conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-10691278 on NIH RePORTER |
What this research studies
This research focuses on developing advanced mass spectrometry techniques to analyze large biomolecular assemblies that are crucial for cellular function. By utilizing a novel charge detection method, the project aims to provide detailed information about the mass and structure of these large molecules, which are often targets for therapeutic interventions. The approach allows for simultaneous analysis of multiple ions, overcoming limitations of traditional methods that struggle with high mass and complexity. This could enhance our understanding of cellular processes and improve the development of targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that involve large biomolecular assemblies, such as certain cancers or genetic disorders.
Not a fit: Patients with conditions unrelated to large biomolecular structures or those not requiring advanced therapeutic interventions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better therapeutic strategies by providing insights into the structure and function of large biomolecules involved in various diseases.
How similar studies have performed: While charge detection mass spectrometry is a relatively novel approach, preliminary studies have shown promise in analyzing large biomolecules, indicating potential for success in this area.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Williams, Evan R — University of California Berkeley
- Study coordinator: Williams, Evan R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.