New technology for measuring cancer cell metabolism in real time
Official title: Acquisition of a calScreener Isothermal Microcalorimetry System for Translational Cancer Metabolism Research at Roswell Park
Funded at Roswell Park Cancer Institute Corp · NIH-10632401 · Data updated 2026-11-12
This study is looking to use a special machine that can measure the heat produced by living cancer cells in real-time, helping researchers learn more about how these cells work and respond to treatments, which could lead to better therapies for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Roswell Park Cancer Institute Corp NIH-funded |
| Lab location | 1 site (Buffalo, United States) |
| Project start | July 15, 2023 |
| Project end | July 14, 2025 |
| Funding year | 2023 |
| Award (this year) | $310,000 |
| NIH project number | 1S10OD034359-01 |
| Project ID | NIH-10632401 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with various types of cancer who may benefit from advancements in cancer metabolism therapies.
✕Less likely to help
Patients with non-cancerous conditions or those not involved in metabolic research may not receive direct benefits from this research.
What this research studies
This research aims to acquire a calScreener Isothermal Microcalorimetry System, which allows for real-time measurement of heat production from living cells, including cancer cells. By using this innovative technology, researchers can continuously monitor cellular metabolism without disrupting the cells or tissues, providing valuable insights into cancer biology and immunology. The system is versatile and can be applied to various cell types and experimental conditions, enhancing the understanding of how cancer cells behave and respond to treatments. This approach could lead to more effective therapies and improved patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding cancer metabolism, potentially resulting in more effective cancer treatments.
How similar studies have gone: While similar technologies exist, the calScreener represents a novel approach that has not been widely tested in the context of cancer metabolism research.
Where this research is happening
-
Roswell Park Cancer Institute Corp
Buffalo, United States Active
Researchers
- Principal investigator: Repasky, Elizabeth a — Roswell Park Cancer Institute Corp
- Study coordinator: Repasky, Elizabeth a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.