New technology for mapping brain circuits and connectivity
Official title: Hybrid TMS/MRI system for regionally tailored causal mapping of human cortical circuits and connectivity
Funded at Massachusetts General Hospital · NIH-10929483 · Data updated 2026-11-12
This study is exploring a new way to use brain stimulation and imaging together to better understand how different parts of the brain work and connect, which could help improve treatments for people with neurological conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 15, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $385,026 |
| NIH project number | 5UG3EB034875-02 |
| Project ID | NIH-10929483 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with neurological conditions or those interested in understanding brain function and connectivity.
✕Less likely to help
Patients with severe cognitive impairments or those unable to undergo MRI or TMS procedures may not benefit from this research.
What this research studies
This research focuses on developing a hybrid system that combines transcranial magnetic stimulation (TMS) with advanced MRI techniques to create detailed maps of brain circuits. By using a new coil array, the study aims to stimulate specific areas of the brain while simultaneously imaging them, allowing researchers to observe how different brain regions interact. This innovative approach promises to enhance our understanding of brain connectivity and plasticity, which could lead to better-targeted treatments for neurological conditions. Patients may benefit from insights gained through this research, particularly in understanding brain function and potential therapeutic applications.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for diagnosing and treating neurological disorders by providing a clearer understanding of brain connectivity.
How similar studies have gone: Previous research has shown promise in using TMS and MRI together, but this specific hybrid approach is novel and aims to push the boundaries of current methodologies.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Stockmann, Jason P — Massachusetts General Hospital
- Study coordinator: Stockmann, Jason P
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.