New technology for faster and more accurate cancer diagnosis using digital imaging.
Official title: Commercial Readiness for Direct-to-Digital Pathology
Funded at Applikate Technologies, INC. · NIH-10931395 · Data updated 2026-11-12
This study is testing a new way to quickly and accurately look at biopsy samples for cancer using a special imaging technology, so patients can get their results on the same day without the usual lengthy preparation.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Applikate Technologies, INC. NIH-funded |
| Lab location | 1 site (Weston, United States) |
| Project start | January 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,615,322 |
| NIH project number | 5R44CA189522-06 |
| Project ID | NIH-10931395 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults undergoing biopsy procedures for cancer diagnosis.
✕Less likely to help
Patients who do not require biopsy procedures or those with conditions not related to cancer may not benefit from this research.
What this research studies
This research focuses on a novel imaging platform called Clearing Histology with Multiphoton Microscopy (CHiMP), which allows for direct-to-digital imaging of biopsy specimens without traditional slide preparation methods. By eliminating the need for wax embedding and slicing, this technology aims to provide same-day cancer diagnoses, reducing errors and costs associated with current practices. The project also includes developing necessary quality management systems and validation testing for FDA approval, ensuring the technology meets clinical standards. Patients will benefit from quicker results and potentially more accurate diagnoses.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate cancer diagnoses for patients.
How similar studies have gone: Similar approaches in digital pathology have shown promise, indicating potential for success with this novel technology.
Where this research is happening
-
Applikate Technologies, INC.
Weston, United States Active
Researchers
- Principal investigator: Levene, Michael John — Applikate Technologies, INC.
- Study coordinator: Levene, Michael John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.