New technology for detecting brain chemicals and electrical activity at the same time
Dual-function Carbon Modified-Silicon Microelectrodes for Biomolecule Detection with Fast Scan Cyclic Voltammetry and Electrophysiology Recording and Stimulation
['FUNDING_OTHER'] · SPIKE NEURO LLC · NIH-10918896
This study is working on a new device that can measure brain chemicals and electrical activity at the same time, which could help us understand and treat conditions like Parkinson's disease and depression better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SPIKE NEURO LLC (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-10918896 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced microelectrodes that can simultaneously measure both neurochemical signals and electrical activity in the brain. By using a technique called Fast-Scan Cyclic Voltammetry, the researchers aim to create a device that can detect multiple neurotransmitters, such as dopamine and serotonin, while also recording electrical signals from neurons. This dual-function approach could lead to better understanding and treatment of neurological disorders like Parkinson's disease and depression. The project is led by Dr. Alexandros Zestos at SPIKE NEURO LLC in Ann Arbor, where innovative carbon-based materials are being utilized to enhance the sensitivity and accuracy of these measurements.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from neurological conditions such as Parkinson's disease, depression, or those affected by drug abuse.
Not a fit: Patients with neurological disorders that do not involve neurotransmitter imbalances or electrical activity changes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and treatment options for patients with neurological disorders.
How similar studies have performed: Previous research has shown promise in using similar dual-function technologies for neurochemical and electrophysiological measurements, indicating a potential for success in this novel approach.
Where this research is happening
ANN ARBOR, UNITED STATES
- SPIKE NEURO LLC — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZESTOS, ALEXANDROS GEORGE — SPIKE NEURO LLC
- Study coordinator: ZESTOS, ALEXANDROS GEORGE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.