New technology for analyzing proteins in small biological samples
Next-generation nanoflow LC column technology to enable high sensitivity proteomics of limited samples
['FUNDING_OTHER'] · MIXEDLCMEDIA LLC · NIH-11008274
This study is working on a new way to analyze tiny amounts of blood and tissue samples to better understand diseases like Alzheimer's, which could help doctors find new ways to diagnose and treat patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MIXEDLCMEDIA LLC (nih funded) |
| Locations | 1 site (WEST NEWTON, UNITED STATES) |
| Trial ID | NIH-11008274 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced nanoflow liquid chromatography technology to analyze proteins in limited biological samples, such as blood and tissue biopsies. By improving the sensitivity of proteomic analysis, the project aims to uncover critical information about diseases like Alzheimer's. The methodology involves using small-volume samples to identify protein structures and interactions that are vital for understanding disease mechanisms and discovering new biomarkers. This approach could lead to more accurate diagnostics and targeted therapies for patients with neurodegenerative conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with early-stage Alzheimer's disease or those at risk of developing the condition.
Not a fit: Patients with advanced Alzheimer's disease or those who do not have any neurodegenerative conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment options for patients with Alzheimer's disease and related conditions.
How similar studies have performed: Previous research has shown promise in using advanced proteomic techniques for analyzing limited samples, indicating potential success for this novel approach.
Where this research is happening
WEST NEWTON, UNITED STATES
- MIXEDLCMEDIA LLC — WEST NEWTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: IVANOV, ALEXANDER R — MIXEDLCMEDIA LLC
- Study coordinator: IVANOV, ALEXANDER R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease