New technology for analyzing proteins in small biological samples
Official title: Next-generation nanoflow LC column technology to enable high sensitivity proteomics of limited samples
Funded at Mixedlcmedia LLC · NIH-11008274 · Data updated 2026-11-12
This study is working on a new way to analyze tiny amounts of blood and tissue samples to better understand diseases like Alzheimer's, which could help doctors find new ways to diagnose and treat patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mixedlcmedia LLC NIH-funded |
| Lab location | 1 site (West Newton, United States) |
| Project start | September 16, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $306,860 |
| NIH project number | 1R41GM156145-01 |
| Project ID | NIH-11008274 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with early-stage Alzheimer's disease or those at risk of developing the condition.
✕Less likely to help
Patients with advanced Alzheimer's disease or those who do not have any neurodegenerative conditions may not benefit from this research.
What this research studies
This research focuses on developing advanced nanoflow liquid chromatography technology to analyze proteins in limited biological samples, such as blood and tissue biopsies. By improving the sensitivity of proteomic analysis, the project aims to uncover critical information about diseases like Alzheimer's. The methodology involves using small-volume samples to identify protein structures and interactions that are vital for understanding disease mechanisms and discovering new biomarkers. This approach could lead to more accurate diagnostics and targeted therapies for patients with neurodegenerative conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment options for patients with Alzheimer's disease and related conditions.
How similar studies have gone: Previous research has shown promise in using advanced proteomic techniques for analyzing limited samples, indicating potential success for this novel approach.
Where this research is happening
-
Mixedlcmedia LLC
West Newton, United States Active
Researchers
- Principal investigator: Ivanov, Alexander R — Mixedlcmedia LLC
- Study coordinator: Ivanov, Alexander R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.