New technology for 3D imaging of tissue samples
Instrumentation platform for 3D pathology with open-top light-sheet microscopy
['FUNDING_R01'] · UNIVERSITY OF WASHINGTON · NIH-10814198
This study is testing a new way to look at tissue samples from biopsies and surgeries that gives doctors a clearer, 3D view of what's happening in the tissues, which could help them make more accurate diagnoses and better treatment plans for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-10814198 on ClinicalTrials.gov |
What this research studies
This research focuses on developing an innovative imaging platform that allows for high-throughput, slide-free 3D histology of biopsy and surgical specimens. By utilizing open-top light-sheet microscopy, the approach aims to provide a more comprehensive view of tissue structures compared to traditional 2D methods. This nondestructive imaging technique preserves valuable biopsy samples for further analysis and offers significant improvements in diagnostic accuracy and efficiency. Patients may benefit from more precise diagnoses and tailored treatment plans based on detailed tissue analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients undergoing biopsies or surgical procedures for cancer or other tissue-related conditions.
Not a fit: Patients who do not require tissue biopsies or those with conditions that do not involve tissue analysis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and better treatment options for patients with various cancers and degenerative disorders.
How similar studies have performed: Other research has shown promising results with advanced imaging techniques, indicating that this approach could lead to significant advancements in pathology.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIU, JONATHAN T.C. — UNIVERSITY OF WASHINGTON
- Study coordinator: LIU, JONATHAN T.C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.