New technologies to monitor pain and opioid use during surgery

Developing novel technologies to monitor nociception and opioid administration during surgery and general anesthesia to minimize postoperative opioid requirements

['FUNDING_OTHER'] · PASCALL SYSTEMS, INCORPORATED · NIH-11012570

This study is working on new tools to help doctors better understand and manage pain during surgery, so they can give just the right amount of pain relief and reduce the chances of long-term reliance on opioids.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorPASCALL SYSTEMS, INCORPORATED (nih funded)
Locations1 site (Boston, UNITED STATES)
Trial IDNIH-11012570 on ClinicalTrials.gov

What this research studies

This research focuses on developing advanced technologies to better monitor pain levels and opioid administration during surgical procedures. By creating new sensors and algorithms, the project aims to provide a more accurate assessment of nociception, which is the body's response to pain. This will help anesthesiologists administer the right amount of opioids, potentially reducing the risk of postoperative pain and long-term opioid dependency. The approach includes using neurophysiological markers and autonomic data to create a comprehensive measure of pain control during surgery.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients undergoing surgical procedures who may require anesthesia and pain management.

Not a fit: Patients who are not undergoing surgery or those who do not require opioid pain management may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to reduced postoperative pain and lower opioid use, decreasing the risk of chronic opioid dependency for surgical patients.

How similar studies have performed: Other research has shown promise in developing monitoring technologies for pain management, but this specific approach is innovative and largely untested.

Where this research is happening

Boston, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.