New technologies to monitor pain and opioid use during surgery
Official title: Developing novel technologies to monitor nociception and opioid administration during surgery and general anesthesia to minimize postoperative opioid requirements
Funded at Pascall Systems, Incorporated · NIH-11012570 · Data updated 2026-11-12
This study is working on new tools to help doctors better understand and manage pain during surgery, so they can give just the right amount of pain relief and reduce the chances of long-term reliance on opioids.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pascall Systems, Incorporated NIH-funded |
| Lab location | 1 site (Boston, UNITED STATES) |
| Project start | September 15, 2020 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $221,325 |
| NIH project number | 3R42DA053075-03S1 |
| Project ID | NIH-11012570 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing surgical procedures who may require anesthesia and pain management.
✕Less likely to help
Patients who are not undergoing surgery or those who do not require opioid pain management may not benefit from this research.
What this research studies
This research focuses on developing advanced technologies to better monitor pain levels and opioid administration during surgical procedures. By creating new sensors and algorithms, the project aims to provide a more accurate assessment of nociception, which is the body's response to pain. This will help anesthesiologists administer the right amount of opioids, potentially reducing the risk of postoperative pain and long-term opioid dependency. The approach includes using neurophysiological markers and autonomic data to create a comprehensive measure of pain control during surgery.
Why it matters
Potential benefit: If successful, this research could lead to reduced postoperative pain and lower opioid use, decreasing the risk of chronic opioid dependency for surgical patients.
How similar studies have gone: Other research has shown promise in developing monitoring technologies for pain management, but this specific approach is innovative and largely untested.
Where this research is happening
-
Pascall Systems, Incorporated
Boston, United States Active
Researchers
- Principal investigator: Le Mau, Tuan — Pascall Systems, Incorporated
- Study coordinator: Le Mau, Tuan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.