New targeted treatments for glioblastoma
Harvard/Stanford GTN Program: Novel targeted therapeutics for glioblastoma
This study is looking for new ways to create small drugs that can reach the brain and help treat adults with glioblastomas and astrocytomas, and patients may have the chance to join early trials to test these promising new treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10911179 on NIH RePORTER |
What this research studies
This research aims to develop innovative small molecule drugs specifically designed to penetrate the brain and treat adult glioblastomas and astrocytomas. The project involves a collaboration between leading institutions, focusing on three main areas: metabolic reprogramming in specific tumor types, targeting abnormal signaling pathways in glioblastoma, and exploring interactions between tumor cells and neurons. Patients may participate in early phase clinical trials that test these new therapies, which are designed to improve treatment outcomes for this aggressive form of brain cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with glioblastoma or astrocytoma, particularly those with specific genetic mutations.
Not a fit: Patients with other types of brain tumors or those who are not adults may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for glioblastoma, potentially improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown promise in developing targeted therapies for glioblastoma, indicating that this approach could yield significant advancements.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Batchelor, Tracy T — Brigham and Women's Hospital
- Study coordinator: Batchelor, Tracy T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.