New T cell therapy for patients with relapsed acute myeloid leukemia after stem cell transplant

Who could benefit from this research

What this research studies

This research focuses on a novel T cell therapy called MT-401, designed specifically for patients with relapsed acute myeloid leukemia (AML) who have undergone stem cell transplantation. The therapy utilizes T cells that target multiple tumor-associated antigens, which helps to minimize the chances of the cancer escaping treatment. Patients will receive this therapy following a bridging treatment with hypomethylating agents, aiming to enhance the effectiveness of the T cell response. The approach is based on previous findings that show promise in targeting AML cells while sparing healthy tissues.

Why it matters

Where this research is happening

• Marker Therapeutics, INC.
  Houston, United States Active

Researchers

• Principal investigator: Vera, Juan Fernando — Marker Therapeutics, INC.
• Study coordinator: Vera, Juan Fernando

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.