New strategies to prevent bleeding in people with hemophilia A
Targeted, adaptive and time-variant strategies for bleed prevention across the lifespan for persons with hemophilia A
This study is looking for better ways to help kids with hemophilia A avoid bleeding problems by exploring different treatment options, including new medicines and gene therapy, so they can find the safest and most effective choices for their needs.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10949401 on NIH RePORTER |
What this research studies
This research focuses on developing and evaluating new strategies to reduce bleeding risks for individuals with hemophilia A, particularly in children. It aims to create a transparent and independent health economic model that assesses various treatment options, including standard and extended half-life factor products, non-factor substitutes, and gene therapy. By analyzing these options, the research seeks to provide valuable insights into the most effective and equitable treatment strategies for different subpopulations. The project will involve collaboration with experts in health decision science, policy, and hematology.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and young individuals diagnosed with hemophilia A.
Not a fit: Patients with other bleeding disorders or those who do not have hemophilia A may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and better health outcomes for patients with hemophilia A.
How similar studies have performed: Previous research has shown promise in developing treatment strategies for hemophilia A, but this approach aims to create a novel, independent economic model.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Goshua, George — Yale University
- Study coordinator: Goshua, George
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.