New spinal cord stimulation therapy for treating chronic pain without opioids
Official title: The Commercialization of High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic Pain
Funded at Micro-Leads, INC. · NIH-10822401 · Data updated 2026-11-12
This study is testing a new, advanced spinal cord stimulation therapy called HD64 to help people with chronic nerve pain find better relief while reducing the need for pain medications like opioids.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Micro-Leads, INC. NIH-funded |
| Lab location | 1 site (Somerville, UNITED STATES) |
| Project start | September 19, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $400,000 |
| NIH project number | 1SB1NS135787-01 |
| Project ID | NIH-10822401 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic neuropathic pain, particularly those who have not found relief from traditional treatments or are currently dependent on opioids.
✕Less likely to help
Patients with pain conditions that do not respond to spinal cord stimulation or those who are not candidates for surgical intervention may not benefit from this research.
What this research studies
This research focuses on developing a high-resolution spinal cord stimulation therapy called HD64, designed to provide targeted pain relief for individuals suffering from chronic neuropathic pain. The approach utilizes an ultra-thin and conformal lead with multiple stimulation contacts, allowing for more precise targeting of pain pathways in the spinal cord. By improving the effectiveness of spinal cord stimulation, this therapy aims to reduce reliance on opioids, which are often associated with addiction and severe side effects. Patients participating in this research may receive this innovative treatment as part of the clinical evaluation process.
Why it matters
Potential benefit: If successful, this research could significantly improve pain management for patients while reducing their dependence on opioids.
How similar studies have gone: Previous research has shown that spinal cord stimulation can effectively relieve chronic pain, but this specific high-resolution approach is novel and aims to enhance the existing technology.
Where this research is happening
-
Micro-Leads, INC.
Somerville, United States Active
Researchers
- Principal investigator: Mclaughlin, Bryan L — Micro-Leads, INC.
- Study coordinator: Mclaughlin, Bryan L
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.