New spinal cord stimulation therapy for treating chronic pain without opioids

The Commercialization of High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic Pain

NIH-funded research Micro-Leads, INC. · NIH-10822401

This study is testing a new, advanced spinal cord stimulation therapy called HD64 to help people with chronic nerve pain find better relief while reducing the need for pain medications like opioids.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMicro-Leads, INC. NIH-funded
Lab location1 site (Somerville, UNITED STATES)
Project IDNIH-10822401 on NIH RePORTER

What this research studies

This research focuses on developing a high-resolution spinal cord stimulation therapy called HD64, designed to provide targeted pain relief for individuals suffering from chronic neuropathic pain. The approach utilizes an ultra-thin and conformal lead with multiple stimulation contacts, allowing for more precise targeting of pain pathways in the spinal cord. By improving the effectiveness of spinal cord stimulation, this therapy aims to reduce reliance on opioids, which are often associated with addiction and severe side effects. Patients participating in this research may receive this innovative treatment as part of the clinical evaluation process.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from chronic neuropathic pain, particularly those who have not found relief from traditional treatments or are currently dependent on opioids.

Not a fit: Patients with pain conditions that do not respond to spinal cord stimulation or those who are not candidates for surgical intervention may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve pain management for patients while reducing their dependence on opioids.

How similar studies have performed: Previous research has shown that spinal cord stimulation can effectively relieve chronic pain, but this specific high-resolution approach is novel and aims to enhance the existing technology.

Where this research is happening

Somerville, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.