New sensors to detect and analyze protein interactions important for cancer treatment
Official title: Generalizable Nanosensors for Probing Highly Specific Interactions of Protein Kinases
Funded at Syracuse University · NIH-10932918 · Data updated 2026-11-12
This study is working on new tiny sensors that can help doctors see how certain proteins related to cancer behave, which could lead to better and more personalized treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Syracuse University NIH-funded |
| Lab location | 1 site (Syracuse, United States) |
| Project start | September 23, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $397,590 |
| NIH project number | 5R01GM151299-02 |
| Project ID | NIH-10932918 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with hematological malignancies or solid tumors who may benefit from targeted therapies based on protein kinase interactions.
✕Less likely to help
Patients with conditions unrelated to protein kinases or those not undergoing treatment for cancer may not receive any benefit from this research.
What this research studies
This research focuses on developing advanced nanosensors that can identify and quantify the interactions of protein kinases, which are crucial targets for cancer therapies. By creating a new type of sensor that combines a protein recognition ligand with a nanopore, the project aims to generate unique electrical signals that reflect the presence and quantity of specific kinases in a sample. This innovative approach could enhance our understanding of protein interactions in various cancers, potentially leading to improved diagnostic and therapeutic strategies. Patients may benefit from more precise treatments based on the specific protein interactions present in their tumors.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments by improving the detection and analysis of key proteins involved in tumor growth.
How similar studies have gone: While the approach of using nanosensors for protein analysis is innovative, similar technologies have shown promise in other areas of biomedical research, indicating potential for success.
Where this research is happening
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Syracuse University
Syracuse, United States Active
Researchers
- Principal investigator: Movileanu, Liviu — Syracuse University
- Study coordinator: Movileanu, Liviu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.