New screening methods for high-risk women with breast cancer

Chicago Alternative Prevention Study for BReast CAncer in Diverse Populations of High-Risk Women (CAPSBRACA)

NIH-funded research University of Chicago · NIH-10906175

This study is looking for ways to create better breast cancer screening plans for women at high risk, especially those with certain gene mutations or from African backgrounds, to help catch aggressive cancers earlier and improve care for diverse communities in Chicago.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10906175 on NIH RePORTER

What this research studies

This research focuses on developing personalized breast cancer screening strategies for women at high risk, particularly those with BRCA1 and BRCA2 mutations and individuals of African ancestry. It aims to identify women who are at increased risk of aggressive breast cancers that may not be detected through standard screening methods. By utilizing advanced genomic testing and MRI techniques, the study seeks to improve early detection and management of breast cancer in diverse populations. Participants will be recruited from communities of color in Chicago to ensure representation and address health disparities.

Who could benefit from this research

Good fit: Ideal candidates for this research include women with BRCA1 or BRCA2 mutations and those of African ancestry who are at high risk for aggressive breast cancer.

Not a fit: Patients who do not have a family history of breast cancer or do not belong to high-risk groups may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and tailored breast cancer screening protocols that improve outcomes for high-risk women.

How similar studies have performed: Previous studies have shown success in using advanced imaging techniques and genomic testing for breast cancer detection, indicating a promising approach for this research.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.