New screening methods for high-risk women with breast cancer
Official title: Chicago Alternative Prevention Study for BReast CAncer in Diverse Populations of High-Risk Women (CAPSBRACA)
Funded at University of Chicago · NIH-10906175 · Data updated 2026-11-12
This study is looking for ways to create better breast cancer screening plans for women at high risk, especially those with certain gene mutations or from African backgrounds, to help catch aggressive cancers earlier and improve care for diverse communities in Chicago.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | August 11, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $1,167,195 |
| NIH project number | 5R01CA276652-02 |
| Project ID | NIH-10906175 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include women with BRCA1 or BRCA2 mutations and those of African ancestry who are at high risk for aggressive breast cancer.
✕Less likely to help
Patients who do not have a family history of breast cancer or do not belong to high-risk groups may not benefit from this research.
What this research studies
This research focuses on developing personalized breast cancer screening strategies for women at high risk, particularly those with BRCA1 and BRCA2 mutations and individuals of African ancestry. It aims to identify women who are at increased risk of aggressive breast cancers that may not be detected through standard screening methods. By utilizing advanced genomic testing and MRI techniques, the study seeks to improve early detection and management of breast cancer in diverse populations. Participants will be recruited from communities of color in Chicago to ensure representation and address health disparities.
Why it matters
Potential benefit: If successful, this research could lead to more effective and tailored breast cancer screening protocols that improve outcomes for high-risk women.
How similar studies have gone: Previous studies have shown success in using advanced imaging techniques and genomic testing for breast cancer detection, indicating a promising approach for this research.
Where this research is happening
-
University of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Olopade, Olufunmilayo F. — University of Chicago
- Study coordinator: Olopade, Olufunmilayo F.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.