New RNA treatments for lung cancer

Novel bioengineered microRNA therapeutics for lung cancer

NIH-funded research University of California at Davis · NIH-11145167

This research is creating new RNA-based treatments to help people with lung cancer.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-11145167 on NIH RePORTER

What this research studies

Lung cancer is a very serious disease, and we need better ways to treat it, especially the most common type called non-small cell lung cancer (NSCLC). Our bodies naturally produce tiny molecules called microRNAs (miRNAs) that help control how cancer cells grow and spread. When these helpful miRNAs are missing or low in cancer cells, the cancer can get worse. This project is developing a new way to make and deliver these natural, helpful miRNAs back into cancer cells, aiming to stop their growth and spread.

Who could benefit from this research

Good fit: This foundational research is for patients with lung cancer, particularly non-small cell lung cancer, who may benefit from future RNA-based therapies.

Not a fit: Patients without lung cancer would not directly benefit from this specific treatment approach.

Why it matters

Potential benefit: If successful, this work could lead to a new and more effective treatment option for patients with lung cancer.

How similar studies have performed: While the specific bioengineered RNA agents are novel, previous efforts have shown promise in developing this platform technology.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.