New peptides to improve survival after cardiac arrest
Novel peptides for resuscitation
This study is looking at a new treatment using special proteins that might help people who have had a cardiac arrest by improving their chances of survival and recovery during CPR.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project ID | NIH-11133361 on NIH RePORTER |
What this research studies
This research investigates the use of novel peptides to enhance survival rates and neurological outcomes for patients experiencing cardiac arrest. The approach involves administering a specific peptide during cardiopulmonary resuscitation (CPR) to inhibit harmful processes in the heart and brain, potentially improving recovery. The study also explores the role of platelet activation and inflammation in cardiac arrest outcomes, aiming to develop a combined treatment strategy that targets these factors. Patients may benefit from this innovative treatment if it proves effective in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced cardiac arrest and are undergoing resuscitation efforts.
Not a fit: Patients who have not experienced cardiac arrest or those who are not undergoing CPR may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly increase survival rates and improve neurological function in patients who experience cardiac arrest.
How similar studies have performed: Previous studies have shown promising results with similar peptide-based approaches in animal models, indicating potential for success in human applications.
Where this research is happening
Chicago, UNITED STATES
- University of Illinois at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Vanden Hoek, Terry L. — University of Illinois at Chicago
- Study coordinator: Vanden Hoek, Terry L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.