New optical agents to improve brain tumor surgery
Optical Analogs to MRI Contrast Agents for Surgical Guidance of Brain Tumor Resection
['FUNDING_R01'] · DARTMOUTH COLLEGE · NIH-10994062
This study is exploring new ways to help doctors see brain tumors more clearly during surgery, which could lead to better outcomes for patients by making it easier to remove the tumors completely.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DARTMOUTH COLLEGE (nih funded) |
| Locations | 1 site (HANOVER, UNITED STATES) |
| Trial ID | NIH-10994062 on ClinicalTrials.gov |
What this research studies
This research investigates the development of optical analogs to traditional MRI contrast agents to enhance surgical guidance during brain tumor resections. By improving the visibility of tumors during surgery, the goal is to increase the likelihood of complete tumor removal, which is crucial for better patient outcomes. The approach involves using advanced imaging techniques that could provide real-time feedback to surgeons, potentially leading to more accurate and effective surgeries. The research aims to address the limitations of current methods, such as the reliance on gadolinium-based MRI agents and the challenges posed by brain deformation during surgery.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with brain tumors who are scheduled for surgical resection.
Not a fit: Patients with brain tumors that are not operable or those who are not candidates for surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved surgical outcomes for patients with brain tumors by enabling more complete tumor resections.
How similar studies have performed: Similar research efforts have shown promise in enhancing surgical outcomes through improved imaging techniques, indicating a potential for success in this novel approach.
Where this research is happening
HANOVER, UNITED STATES
- DARTMOUTH COLLEGE — HANOVER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DAVIS, SCOTT C — DARTMOUTH COLLEGE
- Study coordinator: DAVIS, SCOTT C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.