New non-opioid treatment for pain management

Novel non-narcotic analgesic for acute and chronic pain

NIH-funded research South Rampart Pharma, LLC · NIH-10819946

This study is testing a new pain medication called SRP-001 that aims to help people with moderate to severe pain without the harmful side effects of traditional pain relievers or the risk of addiction, and it's currently in early trials to see how well it works and how safe it is for patients.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionSouth Rampart Pharma, LLC NIH-funded
Lab location1 site (New Orleans, United States)
Project IDNIH-10819946 on NIH RePORTER

What this research studies

This research focuses on developing SRP-001, a novel non-narcotic medication aimed at treating moderate-to-severe acute and chronic pain. The approach seeks to avoid the harmful side effects associated with traditional pain relievers like acetaminophen and NSAIDs, such as liver and kidney damage, as well as the risk of addiction linked to opioids. Currently, SRP-001 is in Phase 1 clinical trials, where initial data suggests it is safe and has good absorption and effectiveness in the body. The research aims to advance to Phase 2 trials, which will further evaluate its efficacy and safety in a larger patient population.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals suffering from moderate to severe acute or chronic pain who are seeking non-opioid treatment options.

Not a fit: Patients who do not experience moderate to severe pain or those who are already effectively managing their pain with existing treatments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a safer alternative for pain management without the risks associated with current pain medications.

How similar studies have performed: While the approach of developing non-opioid analgesics is gaining traction, the specific formulation of SRP-001 is novel and has not been tested in previous studies.

Where this research is happening

New Orleans, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.