New MRI techniques to predict heart issues in patients with tetralogy of Fallot
Novel Cardiac MRI-Based Predictors for Tetralogy of Fallot: Deformation, Kinematic, and Geometric Analyses
This study is looking to help people who have had surgery for tetralogy of Fallot by using special heart scans to better predict serious heart problems, so doctors can know when to step in and provide the right care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11011367 on NIH RePORTER |
What this research studies
This research focuses on improving the prediction of serious heart complications in patients who have undergone repair for tetralogy of Fallot, a congenital heart defect. By utilizing advanced cardiac MRI techniques, the study aims to develop new metrics that can better assess heart function and predict outcomes such as death and dangerous heart rhythms. The approach involves analyzing heart deformation, movement, and geometry from standard MRI scans, which could lead to more accurate timing for necessary interventions like pulmonary valve replacement. Patients will be monitored to evaluate how these new predictors correlate with clinical outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with repaired tetralogy of Fallot, particularly those at risk for serious heart complications.
Not a fit: Patients without a history of tetralogy of Fallot or those who have not undergone surgical repair for this condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate predictions of heart complications, allowing for timely interventions that could save lives.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for cardiac assessments, suggesting that this approach could yield significant advancements in patient care.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Tandon, Animesh — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Tandon, Animesh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.