New MRI techniques to monitor prostate cancer treatment response
Official title: Hyperpolarized C-13 MRI Techniques to Monitor Radiation Therapy Response in Prostate Cancer Patients
Funded at University of California, San Francisco · NIH-10866527 · Data updated 2026-11-12
This study is looking at a new type of MRI that uses a special substance to help doctors see how prostate cancer patients are doing after radiation therapy, aiming to give a clearer picture of how the cancer is responding and to spot any remaining or worsening disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | July 1, 2021 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $632,659 |
| NIH project number | 5R01CA238379-04 |
| Project ID | NIH-10866527 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are prostate cancer patients undergoing stereotactic body radiation therapy.
✕Less likely to help
Patients with non-prostate cancers or those not receiving radiation therapy may not benefit from this research.
What this research studies
This research investigates advanced MRI techniques using hyperpolarized carbon-13 pyruvate to monitor metabolic changes in prostate cancer patients after radiation therapy. The approach aims to provide a more accurate assessment of cancer response and detect any residual or progressive disease. By utilizing 3D imaging and combining it with multiparametric MRI, the study seeks to address the limitations of current imaging methods, which often fail to identify significant cancer activity post-treatment. This innovative technique could lead to better treatment outcomes and reduced side effects for patients.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring of prostate cancer treatment, allowing for more personalized and effective patient care.
How similar studies have gone: Previous studies using hyperpolarized MRI techniques have shown promising results in detecting metabolic changes in cancer, indicating potential for success in this research.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Vigneron, Daniel B — University of California, San Francisco
- Study coordinator: Vigneron, Daniel B
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.