New MRI technique to evaluate joint inflammation in osteoarthritis
Official title: Novel Non-Contrast MRI to Assess Synovitis in Osteoarthritis
Funded at Stanford University · NIH-11076692 · Data updated 2026-11-12
This study is testing a new type of MRI that can help see joint inflammation in people with osteoarthritis without using any contrast dye, making it safer for patients, and aims to better understand how this inflammation affects the disease and its treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | April 19, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $562,793 |
| NIH project number | 5R01AR083018-02 |
| Project ID | NIH-11076692 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with osteoarthritis, particularly those experiencing knee pain and inflammation.
✕Less likely to help
Patients with osteoarthritis who do not have significant synovitis or those who are not experiencing knee-related symptoms may not benefit from this research.
What this research studies
This research focuses on developing a novel non-contrast MRI method to assess synovitis, which is inflammation of the joint lining, in patients with osteoarthritis (OA). The study aims to improve the ability to visualize and understand the role of synovitis in OA progression and treatment response without the need for contrast agents, which can pose risks for some patients. By utilizing advanced imaging techniques, the research seeks to provide clearer insights into the disease's mechanisms and potentially guide more effective treatment strategies. Patients participating in this research may undergo MRI scans that help identify inflammation in their joints more accurately.
Why it matters
Potential benefit: If successful, this research could lead to better diagnosis and management of osteoarthritis, improving patient outcomes and quality of life.
How similar studies have gone: Previous research has shown promise in using advanced MRI techniques for imaging joint conditions, indicating potential for success in this novel approach.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Kogan, Feliks — Stanford University
- Study coordinator: Kogan, Feliks
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.