New MRI method to assess treatment response in brain tumors
Official title: Development of a Clinical CEST MR Fingerprinting Method for Treatment Response Assessment in Brain Metastases
Funded at Sloan-Kettering Inst Can Research · NIH-10814916 · Data updated 2026-11-12
This study is testing a new MRI method that helps doctors see how brain tumors respond to treatment by providing detailed information about the tumors, which could lead to better care for patients.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | April 1, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $658,526 |
| NIH project number | 5R37CA262662-03 |
| Project ID | NIH-10814916 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with brain metastases who are undergoing treatment.
✕Less likely to help
Patients with non-cancerous brain conditions or those not receiving treatment for brain metastases may not benefit from this research.
What this research studies
This research focuses on developing a novel MRI technique called Chemical Exchange Saturation Transfer (CEST) magnetic resonance fingerprinting to better evaluate how brain metastases respond to treatment. By using specific radio-frequency pulses, the method aims to provide detailed information about the chemical environment of tumors, including pH levels and protein concentrations. This could help distinguish between tumor progression and treatment effects, ultimately leading to more accurate assessments of patient conditions. The approach seeks to overcome current limitations in imaging quality and data processing time.
Why it matters
Potential benefit: If successful, this research could lead to more precise monitoring of brain tumor treatments, improving patient outcomes.
How similar studies have gone: Previous studies have shown promise in using CEST MRI techniques for tumor imaging, indicating potential for success in this novel application.
Where this research is happening
-
Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Cohen, Ouri — Sloan-Kettering Inst Can Research
- Study coordinator: Cohen, Ouri
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.