New mouse models to understand hepatitis B virus infection
Novel mouse models of hepatitis B virus infection and replication
['FUNDING_R01'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-11123189
This study is creating special mouse models to help scientists learn more about how hepatitis B virus (HBV) stays in the body and to find new treatments that could help the millions of people living with this virus.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (WINSTON-SALEM, UNITED STATES) |
| Trial ID | NIH-11123189 on ClinicalTrials.gov |
What this research studies
This research focuses on developing novel mouse models to study hepatitis B virus (HBV) infection and replication. By creating these models, researchers aim to better understand how HBV persists in the body and to identify new antiviral therapies that could effectively eliminate the virus. The study will utilize advanced cell culture techniques and explore the role of specific receptors involved in HBV infection. This approach is crucial for discovering new treatments for the millions of people already infected with HBV.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are chronically infected with hepatitis B virus and are seeking new treatment options.
Not a fit: Patients who are not infected with hepatitis B virus or those who have already achieved a complete cure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective antiviral therapies that eliminate hepatitis B virus infection.
How similar studies have performed: Other research has shown promise in developing antiviral therapies for hepatitis B, but this approach using novel mouse models is relatively new and untested.
Where this research is happening
WINSTON-SALEM, UNITED STATES
- WAKE FOREST UNIVERSITY HEALTH SCIENCES — WINSTON-SALEM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LUO, GUANGXIANG GEORGE — WAKE FOREST UNIVERSITY HEALTH SCIENCES
- Study coordinator: LUO, GUANGXIANG GEORGE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.