New microscopy techniques for imaging cells in 3D environments
Official title: Transformative lightsheet microscopy techniques for subcellular imaging in physiologically relevant 3D environments
Funded at University of New Mexico · NIH-10911102 · Data updated 2026-11-12
This study is working on new ways to take quick and gentle pictures of living cells and tissues to better understand how they behave, especially in tumor environments, which could help find new treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Mexico NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $356,759 |
| NIH project number | 5R35GM151152-02 |
| Project ID | NIH-10911102 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve complex cellular interactions, such as cancer patients.
✕Less likely to help
Patients with conditions that do not involve significant cellular interactions or those who are not undergoing treatment may not benefit from this research.
What this research studies
This research focuses on developing advanced microscopy techniques that allow for fast and minimally invasive imaging of biological processes within living cells and tissues. By utilizing lightsheet microscopy, the project aims to overcome current limitations in imaging speed, resolution, and depth of penetration, which are crucial for studying complex biological interactions, such as those occurring in tumor environments. The approach combines innovative imaging methods to capture dynamic cellular interactions over various time scales, providing insights into cellular behavior and potential therapeutic targets.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of cellular interactions in diseases, potentially guiding more effective treatments.
How similar studies have gone: Other research has shown promise with advanced imaging techniques, suggesting that this approach could lead to significant breakthroughs in understanding cellular dynamics.
Where this research is happening
-
University of New Mexico
Albuquerque, United States Active
Researchers
- Principal investigator: Chakraborty, Tonmoy — University of New Mexico
- Study coordinator: Chakraborty, Tonmoy
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.