New microscopy techniques for better imaging of fatty tissues
Official title: Ultra-broadband multimodal microscopy with a catadioptric lens
Funded at Trestle Optics LLC · NIH-10600776 · Data updated 2026-11-12
This study is working on new ways to take clearer pictures of fatty tissues in the body, which could help doctors better understand and diagnose conditions related to fat, ultimately benefiting patients by improving how these diseases are detected and monitored.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Trestle Optics LLC NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | August 3, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $290,536 |
| NIH project number | 1R43GM149018-01 |
| Project ID | NIH-10600776 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions related to adipose tissue, such as obesity or metabolic disorders.
✕Less likely to help
Patients with conditions unrelated to fatty tissues or those who do not require advanced imaging techniques may not benefit from this research.
What this research studies
This research focuses on developing advanced microscopy techniques that utilize a special type of lens to improve imaging of biological tissues, particularly fatty tissues. The approach aims to overcome limitations of traditional optical microscopes, which struggle with certain types of imaging due to chromatic aberrations and other optical issues. By using an all-reflective lens system, the researchers hope to enhance the clarity and detail of images captured from tissues, which could lead to better understanding and diagnosis of conditions related to adipose tissue. Patients may benefit from improved imaging techniques that could enhance the detection and monitoring of diseases associated with fatty tissues.
Why it matters
Potential benefit: If successful, this research could lead to more accurate imaging techniques that improve diagnosis and treatment of conditions related to fatty tissues.
How similar studies have gone: While the use of advanced microscopy techniques is well-established, the specific application of this all-reflective lens system in biological imaging is relatively novel and has not been widely tested.
Where this research is happening
-
Trestle Optics LLC
Irvine, United States Active
Researchers
- Principal investigator: Hanninen, Adam M — Trestle Optics LLC
- Study coordinator: Hanninen, Adam M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.