New methods to understand metabolic issues in pulmonary hypertension
Official title: Novel Approaches to Assess Metabolic Dysregulation in Pulmonary Hypertension
Funded at Veterans Health Administration · NIH-10951507 · Data updated 2026-11-12
This study is looking at how pulmonary hypertension affects the way your body processes energy, using blood platelets to help understand these changes, so we can find better treatments for people living with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Decatur, UNITED STATES) |
| Project start | October 1, 2023 |
| Project end | September 30, 2028 |
| Funding year | 2025 |
| NIH project number | 5IK2BX005913-02 |
| Project ID | NIH-10951507 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with pulmonary hypertension, particularly those with underlying heart or lung diseases.
✕Less likely to help
Patients without pulmonary hypertension or those with unrelated conditions may not benefit from this research.
What this research studies
This research investigates the metabolic dysregulation associated with pulmonary hypertension (PH), a serious condition affecting blood vessels in the lungs. By analyzing blood platelets as biosensors, the study aims to uncover the underlying metabolic dysfunctions that contribute to the progression of PH. The research will utilize advanced bioinformatics to correlate these metabolic changes with clinical features of the disease, potentially leading to better-targeted therapies. Patients with PH may have their metabolic profiles assessed to understand their condition better and explore new treatment options.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted therapies for patients suffering from pulmonary hypertension.
How similar studies have gone: Previous research has shown promise in using metabolic assessments to understand various diseases, suggesting that this approach could yield valuable insights for pulmonary hypertension as well.
Where this research is happening
-
Veterans Health Administration
Decatur, United States Active
Researchers
- Principal investigator: Smith, Matthew Ryan — Veterans Health Administration
- Study coordinator: Smith, Matthew Ryan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.