New methods to test for antibodies against COVID-19 using dried blood samples
High-Throughput Dried Blood Spot (HT-DBS) Technologies in SARS COV-2 Serology and Vaccinology
['FUNDING_U01'] · WADSWORTH CENTER · NIH-10855042
This study is looking at new ways to test large groups of people for antibodies to the COVID-19 virus, using a special method that checks both how many antibodies you have and how well they work, so we can better understand how the community has been affected by the virus and improve our response to outbreaks.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WADSWORTH CENTER (nih funded) |
| Locations | 1 site (MENANDS, UNITED STATES) |
| Trial ID | NIH-10855042 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced technologies to screen large populations for antibodies to SARS-CoV-2, the virus responsible for COVID-19. By utilizing dried blood spots and a specialized immunoassay, the project aims to measure both the quantity and quality of antibodies resulting from natural infections and vaccinations. This approach will enhance our understanding of community exposure to the virus and help predict outbreak dynamics. The goal is to implement high-throughput testing that can efficiently assess antibody responses across diverse populations.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals who have been exposed to SARS-CoV-2 or have received a COVID-19 vaccine.
Not a fit: Patients who have not been exposed to SARS-CoV-2 and have not received a vaccine may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for monitoring COVID-19 exposure and vaccine effectiveness in the general population.
How similar studies have performed: Other research has shown promise in using similar serological testing approaches for monitoring viral infections, indicating potential success for this novel application.
Where this research is happening
MENANDS, UNITED STATES
- WADSWORTH CENTER — MENANDS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MANTIS, NICHOLAS J. — WADSWORTH CENTER
- Study coordinator: MANTIS, NICHOLAS J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.