New methods to separate and analyze RNA carriers in the body
Novel Separation Methods for exRNA Carriers: Extracellular Vesicles, Lipoprotein Particles, and Protein Aggregates
['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-10483185
This study is exploring new ways to collect and study tiny particles in our body that carry important RNA information, which could help doctors better understand health and diseases, leading to improved tests for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10483185 on ClinicalTrials.gov |
What this research studies
This research focuses on developing innovative techniques to isolate and analyze different types of extracellular RNA (exRNA) carriers, such as extracellular vesicles, lipoprotein particles, and protein aggregates. By using advanced physical and biochemical separation methods, the team aims to ensure that these carriers are accurately profiled without contamination. The goal is to create a comprehensive library of data on these carriers, which could enhance our understanding of their roles in health and disease. Patients may benefit from improved diagnostic methods based on the analysis of exRNA.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals undergoing diagnostic evaluations for conditions that may be linked to exRNA biomarkers.
Not a fit: Patients with conditions unrelated to exRNA or those not undergoing diagnostic evaluations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate liquid biopsy techniques for diagnosing various diseases.
How similar studies have performed: Previous research has shown promise in using similar separation techniques for analyzing exRNA, indicating potential for success in this novel approach.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WITWER, KENNETH W — JOHNS HOPKINS UNIVERSITY
- Study coordinator: WITWER, KENNETH W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.