New methods to reduce inflammation caused by air pollution exposure
Novel Approaches for Improving Inflammation Resolution Following Chronic Exposure to Air Pollutants
This study is looking at how long-term exposure to air pollution can cause ongoing inflammation in the body, which might lead to diseases like Alzheimer's, and it aims to find new ways to help the body heal from this inflammation, potentially leading to better treatments for people dealing with related health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11003295 on NIH RePORTER |
What this research studies
This research investigates how chronic exposure to air pollutants leads to unresolved inflammation, which can contribute to various chronic diseases, including Alzheimer's disease. The team will explore two novel pathways that may help resolve inflammation more effectively. By studying the role of specific molecules in macrophages, the research aims to understand how to enhance the body's natural ability to heal and repair tissues affected by environmental toxins. Patients may benefit from insights that could lead to new treatments for inflammation-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with chronic inflammatory conditions or those exposed to high levels of air pollution.
Not a fit: Patients who do not have chronic inflammatory conditions or who are not exposed to air pollutants may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve inflammation resolution and potentially reduce the risk of chronic diseases linked to air pollution.
How similar studies have performed: Other research has shown promise in understanding inflammation resolution, but this approach is exploring novel pathways that have not been extensively tested.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Reddy, Srinivasa T. — University of California Los Angeles
- Study coordinator: Reddy, Srinivasa T.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.