New methods to identify brain areas involved in epilepsy
Novel diagnostic stimulation to quantify cortical excitability and guide epilepsy therapy
This study is looking for ways to better diagnose and treat focal epilepsy by using special electrical stimulation techniques to pinpoint the exact areas in the brain that trigger seizures, helping to create more effective treatments just for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10889026 on NIH RePORTER |
What this research studies
This research focuses on improving the diagnosis and treatment of focal epilepsy by developing innovative stimulation techniques to measure brain excitability. By using multiple pulses of electrical stimulation and advanced waveforms, the study aims to create precise biomarkers that can identify the specific brain regions responsible for initiating seizures. Patients will undergo assessments that involve these stimulation techniques, which will help map the brain's network connections related to epilepsy. The goal is to enhance the understanding of individual seizure networks and improve targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with focal epilepsy who experience seizures that are difficult to control with standard treatments.
Not a fit: Patients with generalized epilepsy or those who do not have focal seizure activity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate identification of seizure onset zones, ultimately improving treatment options for patients with epilepsy.
How similar studies have performed: Previous research has shown promise in using stimulation techniques to map brain activity, suggesting that this approach could yield significant advancements in epilepsy treatment.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Lundstrom, Brian Nils — Mayo Clinic Rochester
- Study coordinator: Lundstrom, Brian Nils
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.