New methods to analyze brain-related particles in blood for Alzheimer's disease
Novel Approaches to Capture, Sorting, and Characterization of CNS-Origin Extracellular Vesicles
This study is working on new ways to test for Alzheimer's disease by looking at tiny particles in your blood, which could help doctors diagnose and monitor the condition more easily and accurately, making it better for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10471286 on NIH RePORTER |
What this research studies
This research focuses on developing innovative tools to diagnose and monitor central nervous system diseases, particularly Alzheimer's disease. By analyzing extracellular vesicles found in blood, which are tiny particles that can provide insights into brain health, the research aims to create reliable tests that can be easily accessed in clinical settings. The approach involves enhancing existing techniques to improve the detection and characterization of these vesicles, potentially leading to better understanding and management of Alzheimer's disease. Patients may benefit from more accurate and non-invasive diagnostic methods that could help in early detection and monitoring of their condition.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults, particularly those showing early signs of cognitive decline or diagnosed with Alzheimer's disease.
Not a fit: Patients with non-CNS related conditions or those who are not elderly may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and non-invasive diagnostic tools for Alzheimer's disease, improving patient care and outcomes.
How similar studies have performed: Previous research has shown promise in using extracellular vesicles for biomarker discovery in Alzheimer's disease, indicating a potential for success with this novel approach.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Witwer, Kenneth W — Johns Hopkins University
- Study coordinator: Witwer, Kenneth W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.