New methods to analyze brain imaging data for understanding substance use in adolescents

Scalable Bayesian methods for big imaging data analysis

NIH-funded research University of Michigan at Ann Arbor · NIH-10892281

This study is looking at how brain scans and different life factors might affect substance use in teenagers, helping us understand more about how their brains develop during this important time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-10892281 on NIH RePORTER

What this research studies

This research focuses on developing advanced statistical methods to analyze large imaging datasets, particularly from the Adolescent Brain Cognitive Development (ABCD) Study. By using innovative Bayesian models, the project aims to explore the relationship between brain imaging data and various social and clinical factors that may influence substance use in adolescents. The approach includes creating models that can simultaneously analyze high-resolution brain images and complex data about the environment and individual health. This could lead to identifying key imaging biomarkers that are linked to substance use patterns, enhancing our understanding of adolescent brain development.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 0-20 years who are participating in the ABCD Study or similar studies focused on brain development.

Not a fit: Patients outside the adolescent age range or those not involved in brain imaging studies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved predictions and interventions for preventing substance use in adolescents.

How similar studies have performed: Other research has shown success in using Bayesian methods for analyzing complex imaging data, indicating a promising approach for this study.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.