New methods for detecting and treating colon cancer
Novel Tools for Colon Cancer Detection and Therapy
['FUNDING_OTHER'] · OMAHA VA MEDICAL CENTER · NIH-11044077
This study is working on new ways to find and treat colorectal cancer, especially in the right side of the colon, by focusing on a protein called Claudin-1 that is important in cancer growth, with the goal of helping patients have better outcomes and lower chances of the cancer coming back.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OMAHA VA MEDICAL CENTER (nih funded) |
| Locations | 1 site (OMAHA, UNITED STATES) |
| Trial ID | NIH-11044077 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the detection and treatment of colorectal cancer (CRC), particularly in the right colon where current methods are less effective. It aims to develop novel tools that enhance the visualization of specific types of polyps and improve surgical outcomes by targeting a protein called Claudin-1, which is linked to cancer progression. By understanding how Claudin-1 behaves in different stages of cancer, the research seeks to reduce the risk of cancer recurrence and improve patient survival rates. Patients may benefit from new diagnostic and therapeutic strategies that could lead to better management of their condition.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for colorectal cancer, particularly those with a history of adenomas or those undergoing screening colonoscopy.
Not a fit: Patients with advanced colorectal cancer who are not candidates for surgical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective detection and treatment options for patients with colorectal cancer, potentially reducing recurrence rates and improving survival.
How similar studies have performed: Previous research has shown promising results in targeting Claudin-1 for cancer treatment, indicating that this approach may have potential for success.
Where this research is happening
OMAHA, UNITED STATES
- OMAHA VA MEDICAL CENTER — OMAHA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DHAWAN, PUNITA — OMAHA VA MEDICAL CENTER
- Study coordinator: DHAWAN, PUNITA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: anti-cancer therapy, cancer in the colon, cancer invasiveness, cancer metastasis