New method to measure oxygen levels in the retina
A novel method for volumetric oxygen mapping in living retina
This study is testing a new imaging tool that can quickly and accurately measure oxygen levels in the retina, which could help doctors better understand and treat eye diseases like diabetic retinopathy and glaucoma.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10796996 on NIH RePORTER |
What this research studies
This research focuses on developing a groundbreaking optical imaging technique to measure oxygen levels in the retina, which is crucial for understanding various retinal diseases like diabetic retinopathy and glaucoma. The team aims to create a novel imaging instrument called the oblique scanning laser ophthalmoscope (oSLO) that can provide detailed 3D maps of oxygen distribution in the eye at high speeds. By utilizing advanced oxygen probes, this method will allow for real-time monitoring of oxygen levels in living tissues, potentially leading to better diagnosis and treatment options for patients with retinal conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with diabetic retinopathy, glaucoma, or other retinal diseases that may be affected by oxygen levels.
Not a fit: Patients with retinal conditions not related to oxygen deficiency or those who do not have access to the required imaging technology may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for patients suffering from retinal diseases linked to oxygen deficiency.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques for retinal analysis, but this specific approach to volumetric oxygen mapping is novel and untested.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Yi, Ji — Johns Hopkins University
- Study coordinator: Yi, Ji
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.