New method for treating lung cancer using a minimally invasive technique
Official title: Novel Minimally Invasive Endobronchial Approach for Lung Cancer Ablation
Funded at Coridea, LLC · NIH-10495201 · Data updated 2026-11-12
This study is testing a new, less invasive treatment for non-small cell lung cancer that uses heat to target tumors in patients who can’t have surgery, making it safer and easier for you to get the care you need.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Coridea, LLC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | April 1, 2019 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $784,016 |
| NIH project number | 5R44CA239829-03 |
| Project ID | NIH-10495201 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with non-small cell lung cancer who are not eligible for surgical resection.
✕Less likely to help
Patients with resectable lung tumors or those with advanced-stage lung cancer may not benefit from this research.
What this research studies
This research focuses on developing a novel endobronchial radio-frequency ablation (RFA) system designed to treat non-small cell lung cancer (NSCLC) in patients who are not candidates for surgery. The approach aims to deliver effective thermal ablation to lung tumors while minimizing risks such as pneumothorax. By integrating air aspiration and irrigation flow with a custom RF generator algorithm, the device seeks to enhance the treatment's effectiveness and safety. Patients will benefit from a less invasive option that can be performed using existing bronchoscopic tools.
Why it matters
Potential benefit: If successful, this research could provide a safer and more effective treatment option for patients with non-small cell lung cancer who cannot undergo traditional surgery.
How similar studies have gone: Previous research has shown promise with minimally invasive techniques for lung cancer treatment, but this specific approach is innovative and has not been widely tested.
Where this research is happening
-
Coridea, LLC
New York, United States Active
Researchers
- Principal investigator: Levin, Howard — Coridea, LLC
- Study coordinator: Levin, Howard
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.