New method for imaging brain blood flow using light
Time-Gated Diffuse Correlation Spectroscopy for functional imaging of the human brain
['FUNDING_U01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10683210
This study is testing a new way to look at brain activity by using light to measure blood flow in the brain, which could help people with neurological conditions understand their health better without any surgery or discomfort.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10683210 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a novel imaging technique called time-gated functional diffuse correlation spectroscopy (fDCS) to monitor brain activity by measuring blood flow changes in the cerebral cortex. By using light to detect how red blood cells scatter, this method aims to provide more accurate and deeper insights into brain function compared to existing technologies. Patients may benefit from this non-invasive approach, which could lead to better understanding and treatment of various neurological conditions. The research involves the use of advanced optical devices to capture real-time data on brain blood flow.
Who could benefit from this research
Good fit: Ideal candidates include individuals of all ages, from children to adults, who may have neurological conditions affecting brain function.
Not a fit: Patients with stable neurological conditions that do not require advanced imaging or monitoring may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and treatment options for patients with neurological conditions.
How similar studies have performed: Previous research has shown promise in using similar optical techniques for brain imaging, indicating potential for success with this novel approach.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FRANCESCHINI, MARIA ANGELA — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: FRANCESCHINI, MARIA ANGELA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.