New iron nanoparticles for advanced imaging techniques.
Transformative Iron Metal Nanoparticles with Controlled Oxidation for Magnetic Particle Imaging.
['FUNDING_R15'] · UNIVERSITY OF TENNESSEE SPACE INSTITUTE · NIH-10730728
This study is testing new tiny iron particles that can change into a different form in the body to help improve medical imaging, making it easier for doctors to see what's happening inside you.
Quick facts
| Phase | ['FUNDING_R15'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TENNESSEE SPACE INSTITUTE (nih funded) |
| Locations | 1 site (TULLAHOMA, UNITED STATES) |
| Trial ID | NIH-10730728 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a novel class of iron nanoparticles that can transition to iron oxide nanoparticles in the body over a controlled timeframe. These nanoparticles will be carefully synthesized and characterized to assess their size, structure, and magnetic properties, which are crucial for their use in medical imaging. The study will also evaluate the biocompatibility of these particles and their effectiveness in enhancing magnetic particle imaging signals. By developing nanoparticles with specific coatings for controlled oxidation, the research aims to improve imaging sensitivity and resolution in mammalian cells.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals requiring advanced imaging techniques for cardiovascular or other related conditions.
Not a fit: Patients who do not require magnetic imaging or have contraindications for iron-based contrast agents may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and sensitive imaging techniques for diagnosing various medical conditions.
How similar studies have performed: Preliminary research has shown promise in developing similar nanoparticles, indicating potential for success in this innovative approach.
Where this research is happening
TULLAHOMA, UNITED STATES
- UNIVERSITY OF TENNESSEE SPACE INSTITUTE — TULLAHOMA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JOHNSON, JACQUELINE A — UNIVERSITY OF TENNESSEE SPACE INSTITUTE
- Study coordinator: JOHNSON, JACQUELINE A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.