New iron nanoparticles for advanced imaging techniques.
Official title: Transformative Iron Metal Nanoparticles with Controlled Oxidation for Magnetic Particle Imaging.
Funded at University of Tennessee Space Institute · NIH-10730728 · Data updated 2026-11-12
This study is testing new tiny iron particles that can change into a different form in the body to help improve medical imaging, making it easier for doctors to see what's happening inside you.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tennessee Space Institute NIH-funded |
| Lab location | 1 site (Tullahoma, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $451,089 |
| NIH project number | 1R15EB034962-01 |
| Project ID | NIH-10730728 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals requiring advanced imaging techniques for cardiovascular or other related conditions.
✕Less likely to help
Patients who do not require magnetic imaging or have contraindications for iron-based contrast agents may not benefit from this research.
What this research studies
This research focuses on creating a novel class of iron nanoparticles that can transition to iron oxide nanoparticles in the body over a controlled timeframe. These nanoparticles will be carefully synthesized and characterized to assess their size, structure, and magnetic properties, which are crucial for their use in medical imaging. The study will also evaluate the biocompatibility of these particles and their effectiveness in enhancing magnetic particle imaging signals. By developing nanoparticles with specific coatings for controlled oxidation, the research aims to improve imaging sensitivity and resolution in mammalian cells.
Why it matters
Potential benefit: If successful, this research could lead to more effective and sensitive imaging techniques for diagnosing various medical conditions.
How similar studies have gone: Preliminary research has shown promise in developing similar nanoparticles, indicating potential for success in this innovative approach.
Where this research is happening
-
University of Tennessee Space Institute
Tullahoma, United States Active
Researchers
- Principal investigator: Johnson, Jacqueline a — University of Tennessee Space Institute
- Study coordinator: Johnson, Jacqueline a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.