New injectable system for managing musculoskeletal pain

Novel injectable analgesic delivery system for musculoskeletal pain management

['FUNDING_R01'] · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · NIH-10852320

This study is testing a new way to deliver pain relief for people with conditions like osteoarthritis and lower back pain, using a special injection that combines numbing medicine with small amounts of anti-inflammatory drugs to help manage pain safely and without the risks of opioids.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CONNECTICUT SCH OF MED/DNT (nih funded)
Locations1 site (FARMINGTON, UNITED STATES)
Trial IDNIH-10852320 on ClinicalTrials.gov

What this research studies

This research focuses on developing a novel injectable delivery system for pain management in patients suffering from musculoskeletal conditions such as osteoarthritis and lower back pain. The approach combines local anesthetics with low doses of anti-inflammatory agents to create long-acting formulations that can provide sustained pain relief without the risks associated with opioids. By using engineered carriers for drug delivery, the study aims to enhance the effectiveness and safety of pain treatment. Patients may benefit from a non-addictive alternative to traditional pain medications.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing acute flare-ups of musculoskeletal pain, such as those with osteoarthritis or post-operative pain.

Not a fit: Patients with chronic pain conditions that do not involve acute flare-ups may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide patients with a safer, non-addictive option for managing acute musculoskeletal pain.

How similar studies have performed: Other research has shown promise in using similar approaches to develop non-opioid pain management strategies, indicating potential for success in this area.

Where this research is happening

FARMINGTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.