New injectable system for managing musculoskeletal pain
Official title: Novel injectable analgesic delivery system for musculoskeletal pain management
Funded at University of Connecticut Sch of Med/dnt · NIH-10852320 · Data updated 2026-11-12
This study is testing a new way to deliver pain relief for people with conditions like osteoarthritis and lower back pain, using a special injection that combines numbing medicine with small amounts of anti-inflammatory drugs to help manage pain safely and without the risks of opioids.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Sch of Med/dnt NIH-funded |
| Lab location | 1 site (Farmington, United States) |
| Project start | August 1, 2019 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $71,425 |
| NIH project number | 3R01AR075143-05S1 |
| Project ID | NIH-10852320 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing acute flare-ups of musculoskeletal pain, such as those with osteoarthritis or post-operative pain.
✕Less likely to help
Patients with chronic pain conditions that do not involve acute flare-ups may not benefit from this research.
What this research studies
This research focuses on developing a novel injectable delivery system for pain management in patients suffering from musculoskeletal conditions such as osteoarthritis and lower back pain. The approach combines local anesthetics with low doses of anti-inflammatory agents to create long-acting formulations that can provide sustained pain relief without the risks associated with opioids. By using engineered carriers for drug delivery, the study aims to enhance the effectiveness and safety of pain treatment. Patients may benefit from a non-addictive alternative to traditional pain medications.
Why it matters
Potential benefit: If successful, this research could provide patients with a safer, non-addictive option for managing acute musculoskeletal pain.
How similar studies have gone: Other research has shown promise in using similar approaches to develop non-opioid pain management strategies, indicating potential for success in this area.
Where this research is happening
-
University of Connecticut Sch of Med/dnt
Farmington, United States Active
Researchers
- Principal investigator: Nair, Lakshmi S — University of Connecticut Sch of Med/dnt
- Study coordinator: Nair, Lakshmi S
Related research
Other NIH-funded projects on the same topics.
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New injectable system for managing musculoskeletal pain
This study is testing a new way to deliver long-lasting pain relief for people with conditions like osteoarthritis and lower back pain, using a special injection that combines local anesthetics with small amounts of anti-inflammatory medicine to help manage pain safely without opioids.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.